Every condition that qualifies for the Florida Medical Marijuana Use Registry, grouped by the 2017 NASEM consensus report evidence tiers. Cross-linked to clinical condition pages where available. Compiled by the Miracle Leaf® physician network.
Statutory authority: Florida Medical Marijuana Use Registry. Patient minimum age: 18. Out-of-state reciprocity: Not honored.
See the full step-by-step process on the Florida medical marijuana card guide.
Conclusive or substantial evidence
Chronic Pain
Pain persisting beyond expected healing time, lasting months or longer. Cannabis and cannabinoids have substantial evidence for treating chronic pain in adults.
Epilepsy
Neurological disorder characterized by recurrent unprovoked seizures. Cannabidiol (CBD) has strong evidence for reducing seizure frequency in two rare childhood epilepsy syndromes (Dravet syndrome and Lennox-Gastaut syndrome) and is FDA-approved as Epidiolex for those indications.
Multiple Sclerosis Spasticity
Patient-reported muscle spasticity in adults with multiple sclerosis. The 2017 NASEM consensus report found substantial evidence that oral cannabinoids improve patient-reported MS spasticity symptoms in adults.
Moderate evidence
Cancer
Group of diseases involving uncontrolled cell growth. Cannabis and cannabinoids have substantial evidence for treating chemotherapy-induced nausea and vomiting (CINV) and moderate evidence for improving sleep disturbance among cancer patients; antitumor effects remain investigational.
HIV/AIDS
Viral infection that progressively weakens the immune system. Cannabis and cannabinoids have moderate evidence for improving appetite and weight gain in HIV/AIDS-associated wasting, and limited evidence for symptomatic relief in HIV-associated peripheral neuropathy.
Terminal Illness
Illness expected to result in death within a defined prognosis window (often six to twelve months). Cannabis has moderate evidence for managing common end-of-life symptoms (pain, nausea, anorexia, anxiety, sleep disturbance) and is a qualifying condition under most state medical cannabis programs without further diagnosis-specific gating.
Limited evidence
Post-Traumatic Stress Disorder
A trauma- and stressor-related disorder that follows exposure to a traumatic event. The 2017 NASEM consensus report found limited evidence that nabilone is effective for improving sleep outcomes in PTSD; broader symptom relief evidence remains limited.
Amyotrophic Lateral Sclerosis (ALS)
Progressive neurodegenerative disease affecting motor neurons. Cannabis has limited evidence for managing spasticity, sleep, pain, and appetite loss in ALS patients; no evidence to date demonstrates disease-modifying effects.
Crohn's Disease
Chronic inflammatory bowel disease affecting any portion of the gastrointestinal tract. Cannabis has limited evidence for symptomatic improvement (pain, sleep, appetite) in Crohn's patients but no evidence for inducing or maintaining clinical remission.
Parkinson's Disease
Progressive neurodegenerative disorder primarily affecting movement. Cannabis has limited evidence for symptomatic relief of tremor, sleep disturbance, and pain in Parkinson's patients; no evidence of disease-modifying or neuroprotective effect to date.
Insufficient evidence
Glaucoma
Group of eye diseases that damage the optic nerve, usually associated with elevated intraocular pressure. Cannabis transiently lowers intraocular pressure, but the effect duration is too short to be clinically useful; the American Academy of Ophthalmology and the American Glaucoma Society do not recommend cannabis as glaucoma treatment.
Diagnosis documentation
Florida physicians evaluate qualifying patients against the statutory criteria during the visit. Bring documentation of your condition from your treating clinician: a recent office note, hospital discharge summary, specialist letter, or radiology or pathology report works in most cases. Miracle Leaf® staff can confirm whether your records meet the program requirement before you schedule the evaluation.
Frequently asked questions
Is recreational marijuana legal in Florida?
No. Possession of 20 grams or less is a misdemeanor (up to one year in jail, $1,000 fine). Larger amounts scale to felony charges. Amendment 3 of 2024 received 56% support but failed Florida's 60% constitutional supermajority. Smart and Safe Florida's 2026 ballot effort did not certify: state officials validated only 793,000 of the ~1.4 million signatures submitted (880,000 required).
Who qualifies for Florida's medical cannabis program?
Patients certified by a qualifying physician for one of ten enumerated conditions under §381.986(2): cancer, epilepsy, glaucoma, HIV/AIDS, PTSD, ALS, Crohn's disease, Parkinson's disease, multiple sclerosis, or terminal illness. Plus a comparable-class clause allowing other conditions of the same kind. Chronic nonmalignant pain caused by a qualifying condition also qualifies.
What can a Florida medical patient possess?
Up to 2.5 ounces of smokable cannabis per 35-day supply window. Non-smokable forms are dispensed up to a 70-day supply. Edibles are capped at 200 mg THC per product and 10 mg THC per serving. Patients must purchase from licensed Medical Marijuana Treatment Centers (MMTCs).
Can Florida medical patients grow their own cannabis?
No. Home cultivation is prohibited under §381.986. All medical cannabis must be purchased from licensed Medical Marijuana Treatment Centers (MMTCs).
Sources and citations
- Florida Statute 381.986: Medical use of marijuana
- Florida Office of Medical Marijuana Use (OMMU)
- NORML: Florida Laws & Penalties
- Marijuana Policy Project: Florida
Last reviewed: 2026-05-17. Evidence tiers reflect the 2017 NASEM consensus report on cannabis and cannabinoids. Not medical advice — consult a licensed clinician.